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Efficient and mild swern oxidation using a new sulfoxide and bis (trichloromethyl)carbonate.
- Source :
-
Synthetic Communications . 2016, Vol. 46 Issue 10, p885-892. 8p. - Publication Year :
- 2016
-
Abstract
- A new type of sulfoxide, 4-(2-(2-(methylsulfinyl) ethyl)-4-nitrophenyl)- morpholine (I), was designed and prepared in good yield. Upon the combination ofIandbis(trichloromethyl)carbonate, the Swern oxidation of primary and secondary alcohols was significantly promoted under mild conditions, which afforded the corresponding aldehydes or ketones in good yields. It is noteworthy that the reoxidation of the isolated by-product sulfide V could be further recycled in Swern oxidation. [ABSTRACT FROM PUBLISHER]
- Subjects :
- *SULFOXIDES
*MORPHOLINE
*KETONES
*OXIDATION
*ALCOHOLS (Chemical class)
Subjects
Details
- Language :
- English
- ISSN :
- 00397911
- Volume :
- 46
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Synthetic Communications
- Publication Type :
- Academic Journal
- Accession number :
- 116170273
- Full Text :
- https://doi.org/10.1080/00397911.2015.1137943