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Osteoclastic-Type Giant Cell Tumours of the Pancreas: A Homogenous Series of Rare Tumours Diagnosed by Endoscopic Ultrasound.

Authors :
Lahiff, Conor
Swan, Niall
Conlon, Kevin
Malone, Dermot
Maguire, Donal
Hoti, Emir
Geoghegan, Justin
McEntee, Gerry
O''Toole, Dermot
Source :
Digestive Surgery. Jun2016, Vol. 33 Issue 5, p401-405. 5p. 2 Diagrams, 1 Chart, 1 Graph.
Publication Year :
2016

Abstract

Background: Giant cell tumors (GCT) of the pancreas are a rare form of pancreatic cancer. Although data are limited, clinical outcomes appear to depend largely on histological subtype with osteoclastic tumors carrying a better prognosis. We report on a homogenous series of patients with osteoclastic- type GCTs of the pancreas presenting to a national pancreatico-biliary gastrointestinal oncology center. Methods: Patients underwent endoscopic, radiological and histopathological assessments. Data were collected in relation to consecutive patients presenting with osteoclastictype tumors of the pancreas and analyzed with survival as a primary end point. Results: Four patients were treated over a 4-year period. Median age was 77 years with equal gender distribution. Median tumor size was 42 mm. Histology was osteoclast-type giant cells in all 4 patients. Two patients underwent surgery with curative intent. Median overall survival was 13.1 months. Conclusion: This is the largest reported series of osteoclast-type histology in GCTs of the pancreas. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02534886
Volume :
33
Issue :
5
Database :
Academic Search Index
Journal :
Digestive Surgery
Publication Type :
Academic Journal
Accession number :
116096082
Full Text :
https://doi.org/10.1159/000445303