综合干预对原发性骨质疏松治疗依从性及生活质量的影响.

Objective: To investigate the effect of comprehensive nursing intervention on the treatment compliance and quality of life for patients with primary osteoporosis(POP) at special consultation clinic. Methods: 112 cases of POP patients admitted to the hospital during May 2010 to May 2013 year as the research object were divided into intervention group and control group, given different nursing measure on the base of drug treatment. After 6 months of intervention, POP knowledge(OKT score), pain(VAS score), bone mineral density(BMD) and quality of life(OQOLS score) of two groups before and after the intervention was compared. After 1 year of intervention, the treatment compliance, the incidence of fracture of two groups was evaluated. Results: After 6 months of intervention, the OKT score, VAS score and BMD of the intervention group were significantly different from before treatment(P<0.001), and there were also statistical difference compared to control group(P<0.001). The OQOLS score of 5 dimensions and total score of life quality in intervention group after intervention were statistically different from before intervention(P<0.001), and also statistically different from control group(P<0.001), while in control group, there was little change on psychological and social dimensions after intervention(P>0.05). Followed up for 1 year, total dependency ratio in intervention group was significantly higher than the control group, and no compliance ratio was lower than the control group(P<0.001); the incidence rate of pathologic fracture in intervention group was lower than control group(P>0.05). Conclusion: Giving comprehensive nursing intervention on the basis of drug treatment for the special consultation clinic patients with primary osteorosis, it can significantly improve the treatment compliance, improve bone mineral density,reduce pain, decrease the incidence rate of pathologic fracture, and improve the quality of life. [ABSTRACT FROM AUTHOR]