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Adverse Drug Reaction in the Neonatal Intensive Care Unit: A Single Center Study.
- Source :
-
Neonatal Medicine . Nov2015, Vol. 22 Issue 4, p187-191. 5p. - Publication Year :
- 2015
-
Abstract
- Purpose: Little research has been conducted on adverse drug reactions in neonates, particularly in Korea, where no studies have been reported. Methods: We conducted a retrospectively study using medical records in a neonatal intensive care unit from August 1, 2013 to July 31, 2014. The adverse drug reactions were evaluated according to the Naranjo algorithm, World Health Organization- Uppsala Monitoring Centre, and the Korean adverse drug reaction algorithm. Results: Of the 410 infants hospitalized during the study period, 57 cases of adverse drug reactions were reported in 40 infants (9.8%). The average gestational age was 28.4±4.3 weeks, the average birth weight was 1,184.1±622.0 g, and the adverse drug reactions were reported at an average of 21.0±29.7 days after birth. Causative agents were identified as electrolytes (36.8%), respiratory medication (14.0%), total parenteral nutrition (12.3%), lipid emulsion (10.5%), antibiotics (7.0%), non-steroidal antiinflammatory drugs (NSAIDs, 7.0%), sedatives (7.0%), vaccine (3.5%), and an antiviral medication (1.8%). Of the 57 cases, 55 (96.5%) cases demonstrated meaningful adverse drug reactions, defined as those given a score of “possible or above” in all 3 adverse drug reaction algorithms. Conclusion: More emphasis is warranted in the field of neonatal adverse drug reactions. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DRUG side effects
*NEONATAL intensive care
*HOSPITAL care
Subjects
Details
- Language :
- Korean
- ISSN :
- 22879412
- Volume :
- 22
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Neonatal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 115905055
- Full Text :
- https://doi.org/10.5385/nm.2015.22.4.187