İdiyopatik Karpal Tünel Sendromunda Lipid Profili Bozuklukları.

Objective: Carpal tunnel syndrome (CTS) is a common entrapment neuropathy caused by compression of the median nerve in carpal tunnel. It is viewed common especially among women, middle-age group and some specific occupational groups. In our study, we investigated whether lipid profile disorders are risk factors for CTS or not. Methods: 52 patients applied to neurosurgery outpatient clinic were accepted to our study between August 2009 and July 2010. After taking medical history, physical examination, laboratory parameters and evaluation of electrophysiological research, patients were diagnosed as "Idiopathic Carpal Tunnel Syndrome" and only the patients taking a surgery indication were accepted to study. 52 healthy individuals without risk factors for CTS evaluated as control group. Questionnaire evaluating medical histories of patients, routine biochemistry analysis and CBC levels were recorded. Results: The mean age was 56.69±12.36 years in CTS group, 50.04±9.40 years in control group. The mean level of lipid parameters in CTS group; total cholesterol (TC) was 225.31±42.64 mg/dL, triglycerides (TG) was 182.85±81.65 mg/dL, LDL cholesterol was 142.77±36.23 mg/dL, HDL cholesterol was 47.71±10.68 mg/dL, respectively. Comparing lipid parameters levels of control group in terms of TC and LDL, statistically significant difference was detected between two groups (p=0.020, p=0.035). Examining the occupational factors that influence to develop for disease, it was found that 80.8% (n=42) of patient group comprised with majority of women was a housewife. Conclusions: In our study, it has been concluded that high TC and LDL values may be a risk factor in etiopathogenesis of CTS. In this sense, in addition to appropriate history and physical examination, hypercholesterolemia should not be forgotten as one of the major modifiable risk factors in women especially housewives that CTS is seen frequently. [ABSTRACT FROM AUTHOR]