Non-linear longitudinal compression effect on dynamics of the transcription bubble in DNA.

The dependence of the dynamics of transcription bubble on the parameters of non-linear longitudinal compression is presented on the base of simple model of soliton-like conformational switchings in two-component bistable polymer molecules with energetically non-equivalent stable states. It has been shown that under certain conditions the longitudinal compression may be a trap for a conformational switching. [ABSTRACT FROM AUTHOR]