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Anti-inflammatory, Analgesic and Antiulcer properties of Porphyra vietnamensis.
- Source :
-
Avicenna Journal of Phytomedicine . Jan/Feb2015, Vol. 5 Issue 1, p69-77. 9p. - Publication Year :
- 2015
-
Abstract
- Objectives: Aim of the present work was to investigate the antiinflammatory, analgesic and antiulcer effects of red seaweed Porphyra vietnamensis (P. vietnamenis). Materials and Methods: Aqueous (POR) and alcoholic (PE) fractions were successfully isolated from P. vietnamenis. Further biological investigations were performed using a classic test of paw edema induced by carrageenan, writhing induced by acetic acid, hot plate method and naproxen induced gastro-duodenal ulcer. Results: Among the fractions POR showed better activity. POR and PE significantly (p < 0.05) reduced carrageenan induced paw edema in a dose dependent manner. In the writhing test POR significantly (p < 0.05) reduced abdominal writhes than PE. In hot plate method POR showed better analgesic activity than PE. POR showed comparable ulcers reducing potential (p<0.01) to that of omeprazole, and has more ulcer reducing potential then PE. Conclusions: The results of this study demonstrated that P. vietnamenis aqueous fraction possesses biological activity that is close to the standards taken for the treatment of peripheral painful or/and inflammatory and ulcer conditions. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANTI-inflammatory agents
*PORPHYRA
*ANALGESIA
Subjects
Details
- Language :
- English
- ISSN :
- 22287930
- Volume :
- 5
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Avicenna Journal of Phytomedicine
- Publication Type :
- Academic Journal
- Accession number :
- 115852423