Afyon Kocatepe Üniversitesi, Araştırma ve Uygulama Hastanesinde takip edilen gebelerde Toksoplazma, Rubella, Sitomegalovirus ve Herpes Simpleks Virus Tip 2 seroprevalansının incelenmesi.

Aim: To determine seroprevalence and presence of IgM and IgG antibodies and IgG avidity levels for Toxoplasma gondii, Cytomegalovirus (CMV), Rubella, Herpes simpleks virus (HSV) 2 and presence of IgM and IgG antibodies against Herpes simplex virus in pregnant women who live in Afyon region. Material and Methods: Toxoplasma gondii IgG- IgM, Cytomegalovirus (CMV)IgG-IgM, Rubella IgG-IgM Herpes simpleks virus2 IgG-IgM antibodies in serum of one 1284 pregnant women who followed by Afyon Kocatepe University medical faculty hospital were detected by Enzyme Immunoassay (EIA) method using VIDAS (Biomerieux / France). HSV type 2 antibodies were detected by EIA method using MiniVIDAS (Biomerieux /France). In addition, CMV IgG avidity tests were measured using VIDAS / Biomerieux France, TOXO IgG avidity tests were measured using VIDAS/ Biomerieux SA/69280 France, RUB IgG avidity tests were measured using Dia.Pro Diagnostic Bioprobes Srl./Via G. Italy. Results: SSeropozitivity of toxoplasma IgG, rubella IgG, CMV IgG, HSV type 2 IgG were detected % 23.4, % 94.5, % 96.0 ve % 7.0 respectively. Seropozitivity of toxoplasma IgM, rubella IgM, CMV IgM, HSV type 2 IgM were detected % 1.5, % 2.5, % 2.3, ve % 1.7 respectively. Furthermore, the values of age, gravida and parity of the pregnant women in the study were calculated as 29.6±7.65 (16-45), 2.18±0.33 (1-6), 1.2±0.78 (0-5) respectively. Conclusion: In this study, TORCH group seropositivity rates are similar Turkey data in pregnant women living in Afyon and around. According to test results, the highest seropositivity rate was found for rubella. The highest seronegativity rate was found to Toxoplasma gondii. IgM follow-up is only advisable for high risk pregnancies due to economic reasons. However, making these screening in pregnancy has a great importance in terms of ending the risky birth. CMV seropositivity was found to be quite high. This status indicates low socioeconomic level in the region. The low seropositivity rates of HSV-2 is an indicator that polygamy is low in region. [ABSTRACT FROM AUTHOR]