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Dose Dependence of the Anticoagulant Effect of Intravenously Administered Cellulose Sulfate.
- Source :
-
Bulletin of Experimental Biology & Medicine . Apr2016, Vol. 160 Issue 6, p767-770. 4p. - Publication Year :
- 2016
-
Abstract
- Experiments on rabbits showed that increasing the dose of intravenously administered cellulose sulfate from wheat straw (dynamic viscosity 3.4 cP, sulfur content 14.1%) increased plasma clotting time in some coagulation tests and plasma anticoagulant activity. When cellulose sulfate was administered in the dose of 1 mg/kg, plasma clotting time in the presence of the anticoagulant (5 min after administration) was ~3-fold higher than after saline administration. [ABSTRACT FROM AUTHOR]
- Subjects :
- *ANTICOAGULANTS
*SULFATES
*CELLULOSE
*WHEAT straw
*VISCOSITY
*DRUG administration
Subjects
Details
- Language :
- English
- ISSN :
- 00074888
- Volume :
- 160
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Bulletin of Experimental Biology & Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 115460537
- Full Text :
- https://doi.org/10.1007/s10517-016-3305-6