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Prognostic importance of new small Q waves following Non–ST-Elevation acute coronary syndromes
- Source :
-
American Journal of Medicine . Dec2003, Vol. 115 Issue 8, p613-619. 7p. - Publication Year :
- 2003
-
Abstract
- : PurposeTo investigate the prognostic importance of new small Q waves following an acute coronary syndrome.: MethodsWe assessed 6-month mortality in 10,501 patients with non–ST-elevation acute coronary syndromes who had survived 30 days and had both admission and 30-day electrocardiograms. Patients were stratified by whether they had no new Q waves (n = 9447), new 30- to 40-ms Q waves (n = 733), or new ≥40-ms Q waves (n = 321).: ResultsMortality was higher in patients with 30- to 40-ms Q waves than in those with no new Q waves (3.4% [25/733] vs. 2.4% [227/9447], P = 0.005), and even higher in those with ≥40-ms Q waves (5.3% [17/321], P = 0.002). After adjustment for baseline risk predictors, mortality remained higher in patients with new 30- to 40-ms Q waves (odds ratio [OR] = 1.30; 95% confidence interval [CI]: 0.85 to 1.98; P = 0.23) and those with new ≥40-ms Q waves (OR = 1.87; 95% CI: 1.13 to 3.09; P = 0.01).: ConclusionPatients with new small Q waves following a non–ST-elevation acute coronary syndrome are at increased risk of adverse outcomes. These small Q waves should be considered diagnostic of myocardial infarction. Further research should investigate whether even smaller QRS changes are prognostically important. [Copyright &y& Elsevier]
- Subjects :
- *PROGNOSIS
*CORONARY disease
*SYNDROMES
*WAVES (Physics)
*ACE inhibitors
*DIAGNOSIS
*CORONARY heart disease treatment
*MYOCARDIAL infarction treatment
*PEPTIDES
*PLATELET aggregation inhibitors
*HEART ventricle diseases
*COMPARATIVE studies
*CONFIDENCE intervals
*CREATINE kinase
*ELECTROCARDIOGRAPHY
*LEFT heart ventricle
*HEART failure
*ISOENZYMES
*RESEARCH methodology
*MEDICAL cooperation
*MYOCARDIAL infarction
*MYOCARDIAL revascularization
*RESEARCH
*SURVIVAL analysis (Biometry)
*SURVIVAL
*EVALUATION research
*ACUTE diseases
*CORONARY angiography
*ODDS ratio
*THERAPEUTICS
MYOCARDIAL infarction diagnosis
MYOCARDIAL infarction-related mortality
Subjects
Details
- Language :
- English
- ISSN :
- 00029343
- Volume :
- 115
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- American Journal of Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 11538214
- Full Text :
- https://doi.org/10.1016/j.amjmed.2003.08.007