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A transformation of cyclopropyl carbene: a highly enantioselective three-component reaction via trapping oxonium ylide by imine.
- Source :
-
Tetrahedron . Jun2016, Vol. 72 Issue 22, p2929-2934. 6p. - Publication Year :
- 2016
-
Abstract
- A transformation of cyclopropyl carbene generated from 2-cyclopropyl-2-diazoacetate via oxonium ylide was found by trapping the resulting ylide with imine. The asymmetric three-component reaction of cycloproyl diazoacetates, benzenemethanols and imines afforded a rapid and efficient method to synthesize complex cyclopropane derivatives with excellent diastereoselectivity and enantioselectivity. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CYCLOPROPYL compounds
*YLIDES
*OXONIUM ions
*CYCLOPROPANE
*IMINES
Subjects
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 72
- Issue :
- 22
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 115211875
- Full Text :
- https://doi.org/10.1016/j.tet.2016.04.006