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Synthesis and characterization of a multimode stationary phase: Congo red derivatized silica in nano-flow HPLC.

Authors :
Zhang, Yi
Zhang, Yan
Wang, Guan
Chen, Wujuan
He, Pingang
Wang, Qingjiang
Source :
Analyst. 2/7/2016, Vol. 141 Issue 3, p1083-1090. 8p.
Publication Year :
2016

Abstract

A novel Congo red (CR) derivatized silica stationary phase was prepared and packed into a fused silica capillary tube for nano-flow HPLC. A variety of analytes including poly-aromatic hydrocarbons, parabens, acids, sulfonamides, bases, and nucleosides were successfully separated using the CR. In comparison with commercial ODS columns, this new stationary phase has a different separation mechanism (hydrophobically-assisted ion-exchange), which was evident in the separation of benzoic acid derivatives and sulfonamides. The successful application of CR-bonded silica stationary phase in the HILIC and PALC modes demonstrates the effectiveness of this potential chromatographic material in nano flow HPLC. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00032654
Volume :
141
Issue :
3
Database :
Academic Search Index
Journal :
Analyst
Publication Type :
Academic Journal
Accession number :
115166023
Full Text :
https://doi.org/10.1039/c5an02021b