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临床试验阶段抗HBV新药的研究现状.

Authors :
李 强
黄玉仙
陈 良
Source :
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi. Feb2016, Vol. 32 Issue 2, p370-373. 4p.
Publication Year :
2016

Abstract

Chronic hepatitis B (CHB) is one of the major causes of liver cirrhosis and hepatocellular carcinoma. Interferon and nucleos(t)ide analogues can control disease progression. However, they cause very low HBsAg clearance or seroconversion rates and relapse in most patients after treatment withdrawal. In recent years, the further understanding of the interaction between hepatitis B virus (HBV) and host gives birth to a large number of novel drugs that hold promise for successful cure of CHB. This paper reviews several novel drugs against HBV in phase I, II, or III clinical trials, and points out that these novel drugs against HBV have preliminarily indicated a bright future. [ABSTRACT FROM AUTHOR]

Details

Language :
Chinese
ISSN :
10015256
Volume :
32
Issue :
2
Database :
Academic Search Index
Journal :
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi
Publication Type :
Academic Journal
Accession number :
114402664
Full Text :
https://doi.org/10.3969/j.issn.1001-5256.2016.02.038