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临床试验阶段抗HBV新药的研究现状.
- Source :
-
Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi . Feb2016, Vol. 32 Issue 2, p370-373. 4p. - Publication Year :
- 2016
-
Abstract
- Chronic hepatitis B (CHB) is one of the major causes of liver cirrhosis and hepatocellular carcinoma. Interferon and nucleos(t)ide analogues can control disease progression. However, they cause very low HBsAg clearance or seroconversion rates and relapse in most patients after treatment withdrawal. In recent years, the further understanding of the interaction between hepatitis B virus (HBV) and host gives birth to a large number of novel drugs that hold promise for successful cure of CHB. This paper reviews several novel drugs against HBV in phase I, II, or III clinical trials, and points out that these novel drugs against HBV have preliminarily indicated a bright future. [ABSTRACT FROM AUTHOR]
Details
- Language :
- Chinese
- ISSN :
- 10015256
- Volume :
- 32
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Clinical Hepatology / Linchuang Gandanbing Zazhi
- Publication Type :
- Academic Journal
- Accession number :
- 114402664
- Full Text :
- https://doi.org/10.3969/j.issn.1001-5256.2016.02.038