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One-pot Synthesis of 5-Unsubstituted 3,4-Dihydropyrimidin-2(1 H )-ones from Aldehydes, Ketones, and Urea under Solvent-free Conditions.
- Source :
-
Polycyclic Aromatic Compounds . 2016, Vol. 36 Issue 3, p242-251. 10p. - Publication Year :
- 2016
-
Abstract
- Various 5-unsubstituted 3,4-dihydropyrimidin-2(1H)-ones were synthesized efficiently by a one-pot three-component condensation of aromatic aldehydes, aromatic ketones, and urea using SnCl2·2H2O as a catalyst under solvent-free conditions. All products were identified by IR, NMR, MS, and elemental analysis. The novel method offers several advantages such as excellent yields (81–95%), short reaction time (5–16 min), broader substrate scope, and environmentally friendly conditions. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYDANTOINASE
*CHEMICAL synthesis
*CHEMICAL reactions
*ALDEHYDES
*KETONES
*UREA
Subjects
Details
- Language :
- English
- ISSN :
- 10406638
- Volume :
- 36
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Polycyclic Aromatic Compounds
- Publication Type :
- Academic Journal
- Accession number :
- 114265021
- Full Text :
- https://doi.org/10.1080/10406638.2014.967785