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7 Tesla quantitative hip MRI: T1, T2 and T2* mapping of hip cartilage in healthy volunteers.

Authors :
Lazik, Andrea
Theysohn, Jens
Geis, Christina
Johst, Sören
Ladd, Mark
Quick, Harald
Kraff, Oliver
Theysohn, Jens M
Johst, Sören
Ladd, Mark E
Quick, Harald H
Source :
European Radiology. May2016, Vol. 26 Issue 5, p1245-1253. 9p. 1 Black and White Photograph, 1 Diagram, 2 Charts, 3 Graphs.
Publication Year :
2016

Abstract

<bold>Objectives: </bold>To evaluate the technical feasibility and applicability of quantitative MR techniques (delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), T2 mapping, T2* mapping) at 7 T MRI for assessing hip cartilage.<bold>Methods: </bold>Hips of 11 healthy volunteers were examined at 7 T MRI with an 8-channel radiofrequency transmit/receive body coil using multi-echo sequences for T2 and T2* mapping and a dual flip angle gradient-echo sequence before (T10) and after intravenous contrast agent administration (T1Gd; 0.2 mmol/kg Gd-DTPA(2-) followed by 0.5 h of walking and 0.5 h of rest) for dGEMRIC. Relaxation times of cartilage were measured manually in 10 regions of interest. Pearson's correlations between R1delta = 1/T1Gd - 1/T10 and T1Gd and between T2 and T2* were calculated. Image quality and the delineation of acetabular and femoral cartilage in the relaxation time maps were evaluated using discrete rating scales.<bold>Results: </bold>High correlations were found between R1delta and T1Gd and between T2 and T2* relaxation times (all p < 0.01). All techniques delivered diagnostic image quality, with best delineation of femoral and acetabular cartilage in the T2* maps (mean 3.2 out of a maximum of 4 points).<bold>Conclusions: </bold>T1, T2 and T2* mapping of hip cartilage with diagnostic image quality is feasible at 7 T. To perform dGEMRIC at 7 T, pre-contrast T1 mapping can be omitted.<bold>Key Points: </bold>• dGEMRIC of hip cartilage with diagnostic image quality is feasible at 7 T. • To perform dGEMRIC at 7 T, pre-contrast T1 mapping can be omitted. • T2(*) mapping of hip cartilage with diagnostic image quality is feasible at 7 T. • T2 and T2* relaxation times of cartilage were highly correlated at 7 T. • Best delineation of femoral and acetabular cartilage was found in T2* maps. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09387994
Volume :
26
Issue :
5
Database :
Academic Search Index
Journal :
European Radiology
Publication Type :
Academic Journal
Accession number :
114245951
Full Text :
https://doi.org/10.1007/s00330-015-3964-0