A new optical window opens for deep brain imaging.

The article focuses on advancements in optical imaging providing benefits towards brain imaging. Topics discussed include role of suitable detectors and femtosecond laser sources in areas of life sciences; ability of multiphoton microscopy to enable deep-tissue imaging by using the ballistic component of near-infrared (NIR) light to excite fluorescence; and emergence of CMOS cameras and photodetectors to improve imaging of blood vessels within the brain.