Chemical constituents from fruiting bodies of Basidiomycete Perenniporia subacida.

Four new aromatic abietane diterpenoids and two new benzene derivatives, namely perenacidins A–F ( 1 – 6 ), have been isolated from the fruiting bodies of Basidiomycete Perenniporia subacida . The structures were elucidated by means of extensive spectroscopic methods and computational ECD method. The antifungal activities against Canidia albicans and the cytotoxic activities against four cancer cell lines (including K-562, A-549, SMMC-7721, MCF-7) were evaluated in vitro . [ABSTRACT FROM AUTHOR]