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Differentiating moderate and severe depression using the Montgomery–A˚sberg depression rating scale (MADRS)
- Source :
-
Journal of Affective Disorders . Dec2003, Vol. 77 Issue 3, p255-260. 6p. - Publication Year :
- 2003
-
Abstract
- Background: MADRS cut-off scores for moderate and severe depression were estimated in relation to the Hamilton Depression Rating Scale (HAMD17) and the Clinical Global Impressions Scale (CGI). Method: HAMD17, MADRS, and CGI ratings from patients with major depression (DSM-IV) were analyzed (<f>N=85</f>). Receiver operating characteristics (ROC) curves were applied. Results: Mean age was 51.4±14.5 years, 69% were female. Mean MADRS scores were 23.4±13.2, HAMD17, MADRS, and CGI scores were highly correlated (<f>r>0.85</f>; P<0.0001). Best separation between moderate and severe depression according to CGI criteria was achieved with a MADRS score of 31 (sensitivity 93.5%, specificity 83.3%). Limitations: Studies to validate severity gradations including DSM-IV or ICD-10 diagnostic severity categories are recommended. Conclusions: Empirically based MADRS cut-off scores to separate moderate from severe depression on the basis of HAMD17 and CGI severity ratings in patients with major depression were yielded. [Copyright &y& Elsevier]
- Subjects :
- *MENTAL depression
*AFFECTIVE disorders
*PATHOLOGICAL psychology
Subjects
Details
- Language :
- English
- ISSN :
- 01650327
- Volume :
- 77
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Affective Disorders
- Publication Type :
- Academic Journal
- Accession number :
- 11322279
- Full Text :
- https://doi.org/10.1016/S0165-0327(02)00120-9