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Different Mid-Term Prognostic Predictors of Major Adverse Events in Diabetic and Nondiabetic Peripheral Artery Disease Presenting With Critical Limb Ischemia.
- Source :
-
Angiology . Mar2016, Vol. 67 Issue 3, p287-291. 5p. - Publication Year :
- 2016
-
Abstract
- We compared midterm prognostic predictors of peripheral artery disease (PAD) with or without diabetes mellitus (DM) presenting with critical lower limb ischemia (CLI). A total of 172 patients with PAD (109 DM; 63 non-DM) were enrolled. The major adverse events (MAEs) were death or amputation. The diabetic group had a higher MAE rate (39% vs 22%, P = .042) with a mean follow-up duration of 30 ± 19 months. In a multivariate binary logistic regression analysis, revascularization (odds ratio = 0.289, P = .006) and higher serum cholesterol (odds ratio=0.988, P = .027) predicted a lower MAE rate in the DM group. In contrast, the presence of severe chronic kidney disease (stage 4 or 5, odds ratio = 5.238, P = .025) was a positive predictor of MAEs in the nondiabetic group. In conclusion, the prognostic predictors of MAE in diabetic and nondiabetic patients with PAD and CLI were different. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DIABETES complications
*KIDNEY disease diagnosis
*AMPUTATION
*CHOLESTEROL
*CONFIDENCE intervals
*FISHER exact test
*GLOMERULAR filtration rate
*ISCHEMIA
*LEG
*MORTALITY
*PERIPHERAL vascular diseases
*RESEARCH funding
*STATISTICS
*T-test (Statistics)
*DATA analysis
*MULTIPLE regression analysis
*CONTRAST media
*RETROSPECTIVE studies
*REVASCULARIZATION (Surgery)
*DATA analysis software
*DESCRIPTIVE statistics
*ODDS ratio
*MANN Whitney U Test
*DISEASE complications
*PROGNOSIS
CHRONIC kidney failure complications
Subjects
Details
- Language :
- English
- ISSN :
- 00033197
- Volume :
- 67
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Angiology
- Publication Type :
- Academic Journal
- Accession number :
- 113107910
- Full Text :
- https://doi.org/10.1177/0003319712475074