Amikacin disulfate: an aminoglycoside antibiotic drug as a corrosion inhibitor for copper in 1 M nitric acid medium.

The effect of commercially available pharmaceutically active compound amikacin disulfate (AMK) against the corrosion of copper in 1 M HNO3solution was investigated using Tafel polarization, electrochemical impedance spectroscopy (EIS), and weight loss techniques. The results show that inhibition efficiency (IE %) increases with increasing inhibitor concentration from 0.1 to 1.0 mM. Increasing the temperature increased the corrosion rate, and results decreased the inhibition efficiency. The adsorption of inhibitor obeyed Langmuir adsorption isotherm model via physisorption mechanism. EIS technique exhibits one capacitive loop, indicating that the corrosion reaction is controlled by charge transfer process. Polarization measurements showed that the AMK is mixed-type inhibitor. The surface morphologies were studied by scanning electron microscopy and atomic force microscopic techniques. The corrosion mechanism were explained by Fourier transform infrared spectroscopy. [ABSTRACT FROM PUBLISHER]