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Preparation of aqueous alpha-lipoic acid dispersions with octenylsuccinylated high amylose starch.
- Source :
-
Carbohydrate Polymers . Apr2016, Vol. 140, p253-259. 7p. - Publication Year :
- 2016
-
Abstract
- Aqueous dispersions prepared with OSA-modified high amylose starch were investigated in comparison with native high amylose starch and beta-cyclodextrin using alpha-lipoic acid as a model substance. Alpha-lipoic acid (ALA), a lipophilic antioxidant essential for energy metabolism in human, was dispersed in gelatinized starch solutions (1.0% w/v) at different temperatures (50–90 °C) and times (3–12 h). High amylose starch modified with 3% OSA (dry starch base) was most favored in maximizing the dispersibility of ALA (84% recovery) under mild heating (70 °C for 3 h). The optimally prepared dispersion was milky white and contained particles with a narrow size distribution (200–300 nm). The precipitate isolated from the dispersion contained crystalline V-complexes of ALA and amylose while the supernatant contained free ALA accounting for 1/3 of total ALA, indicating OSA-modified high amylose starch stabilized ALA either by complexing with amylose or by retarding aggregation of ALA. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 01448617
- Volume :
- 140
- Database :
- Academic Search Index
- Journal :
- Carbohydrate Polymers
- Publication Type :
- Academic Journal
- Accession number :
- 112947176
- Full Text :
- https://doi.org/10.1016/j.carbpol.2015.12.023