Editorial: serotonin and irritable bowel syndrome - reconciling pharmacological effects with basic biology; authors' reply.

The article presents the author's views on the comments given by researcher Quigley EM. on his article "serotonin and irritable bowel syndrome - reconciling pharmacological effects with basic biology". Topics discussed include effect of Serotonin to gut motility and secretion, risk of remaining symptomatic after therapy, Serotonin metabolism, and Bowel pattern over time in Irritable Bowel Syndrome patients.