Raman spectroscopic analysis of dengue virus infection in human blood sera.

We are presenting Raman spectroscopic analysis of dengue virus infection in the human blood sera. Blood samples from 40 individuals infected with dengue virus and 25 healthy volunteers have been used in this study. Raman spectra of all these samples have been acquired in the spectral range from 600 cm −1 to 1750 cm −1 using 532 nm laser as an excitation source. These Raman spectra have been used to analyze the biochemical changes appeared in the blood caused by dengue virus infection. Two Raman lines at 750 cm −1 and 850 cm −1 found in all spectra of dengue infected sera, indicate the presence of adenosine diphosphate (ADP), which is expected to be excreted due to rupturing of thrombocytes. [ABSTRACT FROM AUTHOR]