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Flipping a Lipid-Linked Oligosaccharide? You Must Whip It!

Authors :
Lehrman, Mark A.
Source :
Trends in Biochemical Sciences. Dec2015, Vol. 40 Issue 12, p715-717. 3p.
Publication Year :
2015

Abstract

The mechanism for flipping large lipid-linked oligosaccharides across membranes has remained a paradox. Perez et al. now report the structure of the PglK protein of C. jejuni , a flippase for a bacterial lipid-linked oligosaccharide, and reveal an unexpected whip-like mechanism. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*OLIGOSACCHARIDES
*BACTERIAL lipids
*PROTEIN structure
*CAMPYLOBACTER jejuni
*DOLICHOLS
*BIOCHEMICAL research

Details

Language :
English
ISSN :
09680004
Volume :
40
Issue :
12
Database :
Academic Search Index
Journal :
Trends in Biochemical Sciences
Publication Type :
Academic Journal
Accession number :
111145480
Full Text :
https://doi.org/10.1016/j.tibs.2015.10.001
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