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Invasive assessment of coronary microvascular dysfunction in hypertrophic cardiomyopathy: the index of microvascular resistance.
- Source :
-
Cardiovascular Revascularization Medicine . Oct2015, Vol. 16 Issue 7, p426-428. 3p. - Publication Year :
- 2015
-
Abstract
- We present a review of microvascular dysfunction in hypertrophic cardiomyopathy (HCM) and an interesting case of a symptomatic familial HCM patient with inducible ischemia by single photon emission computed tomography. Coronary angiography revealed normal epicardial arteries. Pressure wire measurements of fractional flow reserve (FFR), coronary flow reserve (CFR) and index of microvascular resistance (IMR) demonstrated a significant microcirculatory dysfunction. This is the first such case that documents this abnormality invasively using the IMR. The measurement of IMR, a novel marker of microcirculatory dysfunction, provides novel insights into the pathophysiology of this condition. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HYPERTROPHIC cardiomyopathy
*MICROCIRCULATION disorders
*PHOTON emission
*COMPUTED tomography
*CORONARY angiography
*PATHOLOGICAL physiology
*ANGIOGRAPHY
*CORONARY arterial radiography
*BLOOD vessels
*CARDIAC catheterization
*CORONARY arteries
*CORONARY circulation
*HEART function tests
*VASCULAR resistance
*MICROCIRCULATION
*SINGLE-photon emission computed tomography
*PREDICTIVE tests
*DIAGNOSIS
Subjects
Details
- Language :
- English
- ISSN :
- 15538389
- Volume :
- 16
- Issue :
- 7
- Database :
- Academic Search Index
- Journal :
- Cardiovascular Revascularization Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 110940964
- Full Text :
- https://doi.org/10.1016/j.carrev.2015.06.008