Pattern of dyslipidemia in ischemic stroke.

The study aimed to assess dyslipidemia pattern including role of non HDL cholesterol (non HDLc) in ischemic strokes. A retrospective descriptive was conducted on 80 patients who were admitted to Osmania General Hospital between May 2013 and May 2015 with new onset of stroke. A detailed history, physical examination and outcome details were collected from the hospital medical records. Data such as fasting lipid profile was noted, non HDLc was calculated, computed tomography (CT) or magnetic resonance imaging (MRI) brain reports were collected from medical records. Among enrolled patients, 55 were males and 25 were females. Age distribution: <40 years, n=4; 40-60 years, n=50; and >60 years, n=26. Dyslipidemia as per ATP III guidelines was present in 92.5% cases (n = 74). In our study, high LDL was found in 16 cases (21.62%), high total cholesterol in 16 cases (21.6%), low HDL in 57 cases (77%), high triglycerides in 13 cases (17.56%) and elevated non HDLc (>130mg/dl) in 28 patients (37.8%). Risk factors for stroke present were hypertension (n=48, 60%), diabetes (n=18, 22.5%), both diabetes and hypertension (n=15, 18.75%), smoking (n=33, 41.25%), alcoholism (n=32, 40%) and more than 2 risk factors were present in 28.75% (n=23). Total number of deaths was 05%. To conclude, most of the patients were having low HDL (<40mg/dL) which is an independent risk factor for stroke. This study also highlights the importance of elevated non HDL Cholesterol in development of ischemic stroke, which is more comprehensive measure of atherogenic lipoprotein than LDL cholesterol alone. This study upholds the importance of life style modifications to cut down the risk of development of stroke and also to evaluate the association between elevated non- HDL cholesterol in stroke patients. [ABSTRACT FROM AUTHOR]