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Synthesis of structural analogs of epibatidine.

Authors :
Babkin, I.
Nazarov, G.
Galan, S.
Yudina, O.
Lamanov, A.
Gutsalyuk, M.
Aksenov, A.
Source :
Russian Chemical Bulletin. Feb2015, Vol. 64 Issue 2, p466-469. 4p.
Publication Year :
2015

Abstract

A convenient one-step method for the preparation of 8-azabicyclo[3.2.1]octan-3-one derivatives, analogs of epibatidine, was suggested, which consists in the reaction of succinic aldehyde with heterocyclic amines and acetonedicarboxylic acid in the presence of sodium hydrogen phosphate. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*DEAMINATION
*AMINES
*ORGANIC compounds
*SODIUM compounds
*ALKALI metals
*HYDROGEN

Details

Language :
English
ISSN :
10665285
Volume :
64
Issue :
2
Database :
Academic Search Index
Journal :
Russian Chemical Bulletin
Publication Type :
Academic Journal
Accession number :
110424662
Full Text :
https://doi.org/10.1007/s11172-015-0888-4
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