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The isolated extranodal relapse of the isolated extranodal non- Hodgkin lymphoma: A case report.
- Source :
-
Journal of Cancer Research & Therapeutics . Jul-Sep2015, Vol. 11 Issue 3, Special section p645-645. 2p. - Publication Year :
- 2015
-
Abstract
- Diffuse large lymphomas of B-cell origin (DLBCL) comprise approximately one-third of all non-Hodgkin lymphomas (NHLs) and extranodal involvement is detected in 50% of these cases at initial diagnosis. Primary malignant lymphoma of the adrenal gland is extremely rare. Here we report a 64-year-old male patient with nasopharyngeal lymphoma who had been in remission for 2 years. An adrenal mass was detected on a control abdominal computed tomography (CT) at one of his follow-up visits. The biopsy showed DLBCL. Since the tumor was solitary without any other nodal involvement, a new/de novo primary tumor was considered. Metachronous NHLs develop between 3 months and 15 years after a primary NHLs and VDJ (variable, diversity, joining) rearrangement gene analysis of the tumor tissue is recommended to discriminate recurrence from a metachronous NHLs. VDJ rearrangement gene analysis was consistent with the recurrence of the original neoplasm. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DIFFUSE large B-cell lymphomas
*CANCER relapse
*LYMPHOMA diagnosis
*ADRENAL gland cancer
*CANCER tomography
*FOLLOW-up studies (Medicine)
*PATIENTS
*ANTINEOPLASTIC agents
*DOXORUBICIN
*VINCRISTINE
*PREDNISONE
*CYCLOPHOSPHAMIDE
*ADRENAL tumors
*B cell lymphoma
*DISEASE complications
*GENETICS
*NASAL tumors
*TREATMENT effectiveness
*THERAPEUTICS
Subjects
Details
- Language :
- English
- ISSN :
- 09731482
- Volume :
- 11
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Cancer Research & Therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 110396040
- Full Text :
- https://doi.org/10.4103/0973-1482.147706