Should the forms of dietary choline also be considered when estimating dietary intake and the implications for health?

Although epidemiological studies suggest that populations are not meeting daily recommendations for total choline, they fail to consider the forms of choline in the diet. Aqueous and lipid-soluble choline forms differ in absorption, metabolism and functions, suggesting that the form matters. It has been demonstrated that the relative amount of these forms of choline can be altered through consuming different foods and using different preparation methods. Evidence suggests that the forms of choline may differentially impact growth, immune function, plasma and serum cholesterol levels and brain development, therefore in addition to estimating the amount total choline in the diet, researchers should also consider what forms of choline are consumed in the diet. [ABSTRACT FROM AUTHOR]