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Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution.

Authors :
Xiao-Wei Hong
Yu-Qiang Zhou
Cui-Bing Bai
Nai-Xing Wang
Yalan Xing
Wei Zhang
Yan-Jing Wang
Xing-Wang Lan
Yu Xie
Yi-He Li
Source :
Molecules. Sep2015, Vol. 20 Issue 9, p17208-17220. 13p. 4 Diagrams, 2 Charts.
Publication Year :
2015

Abstract

An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
14203049
Volume :
20
Issue :
9
Database :
Academic Search Index
Journal :
Molecules
Publication Type :
Academic Journal
Accession number :
110005009
Full Text :
https://doi.org/10.3390/molecules200917208