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MRI with gadoxetate disodium for colorectal liver metastasis: is it the new "imaging modality of choice"?

Authors :
Patel, Shirali
Cheek, Susannah
Osman, Houssam
Jeyarajah, D Rohan
Source :
Journal of Gastrointestinal Surgery. Dec2014, Vol. 18 Issue 12, p2130-2135. 6p.
Publication Year :
2014

Abstract

<bold>Background: </bold>Accurate detection of colorectal liver metastasis is paramount in the role of management. This study aims to compare magnetic resonance imaging (MRI) with gadoxetate disodium (a hepatocyte-specific agent-Eovist®) to triple-phase enhanced computed tomography in detecting colorectal liver metastases.<bold>Methods: </bold>A retrospective chart analysis of 30 patients from 2011 to 2013 with colorectal liver metastases was performed. Patients with more than 6 weeks or two cycles of chemotherapy between the two imaging modalities were excluded. The number of lesions identified on triple-phase enhanced computed tomography vs. MRI with Eovist® was compared.<bold>Results: </bold>Of the 30 patients that met the inclusion criteria, 12 (40 %) patients had more lesions identified on MRI with Eovist® compared to triple-phase enhanced computed tomography. Eighteen (60 %) had no change in the number of lesions identified. When MRI with Eovist® detected more lesions, the mean number of additional lesions detected was 1.5. Eovist® MRI changed the surgical management in 36.7 % of patients.<bold>Conclusion: </bold>MRI with Eovist® is superior to enhanced computed tomography in identifying colorectal liver metastases. The increased number of lesion identified on MRI with Eovist® can profoundly change the surgeon's management. It should be considered the "imaging modality of choice" in preoperative imaging for liver metastases in these patients. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
1091255X
Volume :
18
Issue :
12
Database :
Academic Search Index
Journal :
Journal of Gastrointestinal Surgery
Publication Type :
Academic Journal
Accession number :
109764608
Full Text :
https://doi.org/10.1007/s11605-014-2676-0