Association between a Specific Pneumocystis jiroveci Dihydropteroate Synthase Mutation and Failure of Pyrimethamine/Sulfadoxine Prophylaxis in Human Immunodeficiency Virus--Positive and --Negative Patients.

Authors :: Nahimana, Aimable
Rabodonirina, Meja
Zanetti, Giorgio
Meneau, Isabelle
Francioli, Patrick
Bille, Jacques
Hauser, Philippe M.
Source :: Journal of Infectious Diseases. 10/1/2003, Vol. 188 Issue 7, p1017. 7p.
Publication Year :: 2003
Abstract: Investigates the association between different prophylactic sulfa drugs and the genotype of the Pneumocystis jiroveci dihydropteroate synthase (DHPS) gene. Examination of DHPS polymorphisms in clinical specimens from immunosuppressed patients; Amino acid change at position 57.

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