Electrophilic N-Trifluoromethylation of N-H Ketimines.

A direct N-trifluoromethylation method has been developed by the use of the in situ generated [ArICF3]+ species as the electrophilic trifluoromethyl source. Upon treatment of N-H ketimines with Ruppert-Prakash reagent in the presence of PhI(OAc)2 and KF, or with Togni's reagent II catalyzed by copper salt, N-trifluoromethylated imine products were obtained in moderate to good yields. [ABSTRACT FROM AUTHOR]