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Oxidative stress and anti-oxidant defense system in Iranian women with polycystic ovary syndrome.
- Source :
-
Iranian Journal of Reproductive Medicine . Jun2015, Vol. 13 Issue 6, p373-378. 6p. - Publication Year :
- 2015
-
Abstract
- Background: Polycystic ovary syndrome (PCOS) is a common disorder of infertility which affects more than 100 million women. It is characterized by chronic anovulation, hyper androgenism and obesity. PCOS is also associated with oxidative stress changes. Objective: Here, we aimed to investigate the level of antioxidants and oxidative stress in Iranian women with PCOS as a predictive factor for cardiovascular disease for the first time in Iran. Materials and Methods: In this cross sectional study 30 women with PCOS and 30 healthy women were included. C-reactive protein, serum insulin, advanced oxidation protein products, and level of total antioxidants status were measured from blood samples. Results: The levels of serum insulin, C-reactive protein, advanced oxidation protein productswere significantly increased in women with PCOS compared with healthy women but there was a decrease in level of total antioxidants status in PCOS women. Conclusion: These changes show that oxidative stress contributes to PCOS and the decrease of antioxidants leads to increase of oxidation products contributing to PCOS. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 16806433
- Volume :
- 13
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Iranian Journal of Reproductive Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 109040614