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Association between pulse pressure and risk of hospital admissions for cardiovascular events among people with Type 2 diabetes: a population-based case-control study.
- Source :
-
Diabetic Medicine . Sep2015, Vol. 32 Issue 9, p1201-1206. 6p. 1 Chart, 1 Graph. - Publication Year :
- 2015
-
Abstract
- Aim To investigate the association between pulse pressure and risk of hospitalization for cardiovascular events among people with Type 2 diabetes. Methods A population-based case-control study was carried out using data from medical databases. A total of 588 people with Type 2 diabetes from 18 general practices in Cambridgeshire recorded a first hospitalization for a cardiovascular event between 2009 and 2011, and a total of 2920 age-matched, gender-matched and practice-matched control subjects with Type 2 diabetes were selected based on risk-set sampling. Pulse pressure was assessed before admission in 2008-2009. Further dose-response relationships between pulse pressure and risks were explored using spline models. Results There was a non-linear relationship between pulse pressure and the risk of hospitalization for a cardiovascular event ( P < 0.001 for linearity test). The pulse pressure associated with the lowest risk of hospitalization for a cardiovascular event was 61 (95% CI 57-63) mmHg. Conclusion In people with Type 2 diabetes, pulse pressure is a good predictor of risk of hospitalization for cardiovascular events. The risk is lowest with a pulse pressure of 57-63 mmHg. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CARDIOVASCULAR disease diagnosis
*HOSPITAL admission & discharge
*TYPE 2 diabetes diagnosis
*PATIENTS
*TYPE 2 diabetes complications
*BLOOD pressure
*BLOOD pressure measurement
*CONFIDENCE intervals
*PEOPLE with diabetes
*GLYCOSYLATED hemoglobin
*HIGH density lipoproteins
*LIPOPROTEINS
*LOW density lipoproteins
*NATIONAL health services
*TYPE 2 diabetes
*POPULATION
*PULSE (Heart beat)
*RESEARCH funding
*LOGISTIC regression analysis
*DATA analysis
*BODY mass index
*CASE-control method
Subjects
Details
- Language :
- English
- ISSN :
- 07423071
- Volume :
- 32
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Diabetic Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 108930654
- Full Text :
- https://doi.org/10.1111/dme.12693