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Notch signaling regulates left-right asymmetry determination by inducing Nodal expression.

Authors :
Krebs, Luke T.
Iwai, Naomi
Nonaka, Shigenori
Welsh, Ian C.
Yu Lan
Rulang Jiang
Saijoh, Yukio
O'Brien, Timothy P.
Hamada, Hiroshi
Gridley, Thomas
Source :
Genes & Development. 5/15/2003, Vol. 17 Issue 10, p1207. 6p. 4 Diagrams.
Publication Year :
2003

Abstract

Investigates the role of Notch signaling pathway in the establishment of left-right asymmetry in mice. Regulation of Nodal gene expression; Physiology of the Notch signaling pathway; Presence of Nodal cilia in DII1 mutant embryos; Significance of Nodal gene expression to the determination of left-right axis.

Details

Language :
English
ISSN :
08909369
Volume :
17
Issue :
10
Database :
Academic Search Index
Journal :
Genes & Development
Publication Type :
Academic Journal
Accession number :
10887837
Full Text :
https://doi.org/10.1101/gad.1084703