Anticancer, photoluminescence and electrochemical properties of structurally characterized two imine derivatives.

Two imine compounds, 4-[(E)-(2-methoxybenzylidene)amino]phenol (L 1 ) and 4-[(E)-(3,4-dimethoxybenzylidene)amino]phenol (L 2 ) were synthesized and characterized by the analytical and spectroscopic methods. The electrochemical and photoluminescence properties of the imine compounds L 1 and L 2 were investigated in different solvents. The compounds L 1 and L 2 show different redox processes at some potentials. The molecular structures of two Schiff base compounds are broadly similar, differing principally in the position, the number of methoxy ( OCH 3 ) groups and dihedral angles between aromatic rings. While the compound L 1 has only one methoxy group located on the o -position with respect to the imine bond (C N), the L 2 contains two methoxy groups on the p – m -positions with respect to the imine bond. The imine compounds show two or three emission bands in the 619–832 nm range in organic solvents. In the 1.0 × 10 −3 M concentration, the compounds have the highest excitation and emission bands. The imine compounds L 1 and L 2 were screened for their in vitro cytotoxicity on HeLa cell lines using the xCELLigence system (Real Time Cell Analyzer). [ABSTRACT FROM AUTHOR]