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Characteristics of non-responders to self-reported questionnaires in a large inflammatory bowel disease cohort study.
- Source :
-
Scandinavian Journal of Gastroenterology . Nov2015, Vol. 50 Issue 11, p1348-1356. 9p. - Publication Year :
- 2015
-
Abstract
- Background. A major threat to the validity of longitudinal cohort studies is non-response to follow-up, which can lead to erroneous conclusions. The objective of this study was to evaluate the profile of non-responders to self-reported questionnaires in the Swiss inflammatory bowel disease (IBD) Cohort. Methods. We used data from adult patients enrolled between November 2006 and June 2011. Responders versus non-responders were compared according to socio-demographic, clinical and psychosocial characteristics. Odds ratio for non-response to initial patient questionnaire (IPQ) compared to 1-year follow-up questionnaire (FPQ) were calculated. Results. A total of 1943 patients received IPQ, in which 331 (17%) did not respond. Factors inversely associated with non-response to IPQ were age >50 and female gender (OR = 0.37; p < 0.001 respectively OR = 0.63; p = 0.003) among Crohn's disease (CD) patients, and disease duration >16 years (OR = 0.48; p = 0.025) among patients with ulcerative colitis (UC). FPQ was sent to 1586 patients who had completed the IPQ; 263 (17%) did not respond. Risk factors of non-response to FPQ were mild depression (OR = 2.17; p = 0.003) for CD, and mild anxiety (OR = 1.83; p = 0.024) for UC. Factors inversely associated with non-response to FPQ were: age >30 years, colonic only disease location, higher education and higher IBD-related quality of life for CD, and age >50 years or having a positive social support for UC. Conclusions. Characteristics of non-responders differed between UC and CD. The risk of non-response to repetitive solicitations (longitudinal versus transversal study) seemed to decrease with age. Assessing non-respondents' characteristics is important to document potential bias in longitudinal studies. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00365521
- Volume :
- 50
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Scandinavian Journal of Gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 108698672
- Full Text :
- https://doi.org/10.3109/00365521.2015.1041150