Identification of homozygous deletion in ACAN and other candidate variants in familial classical Hodgkin lymphoma by exome sequencing.

The article offers information on the identification of homozygous deletion in aggrecan (ACAN gene) and other candidate variants in classical Hodgkin lymphoma by exome sequencing. Topics discussed include aetiology of classical Hodgkin lymphoma (CHL), role in CHL tumourigenesis, and association of Epsteinâ€Barr virus (EBV) infection with CHL.