Back to Search
Start Over
Confined chemiluminescence detection of nanomolar levels of H2O2 in a paper–plastic disposable microfluidic device using a smartphone.
- Source :
-
Analyst . 8/7/2015, Vol. 140 Issue 15, p5006-5011. 6p. - Publication Year :
- 2015
-
Abstract
- We report the design and characterization of a disposable light shielded paper–plastic microfluidic device that can detect nanomolar levels of H2O2 using a smartphone camera and a light sealed accessory. Chemiluminescence reaction of H2O2 with bis(2,4,6-trichlorophenyl)oxalate in the presence of rubrene and imidazole is confined to a paper reaction site where the individual reagents are delivered via plastic microfluidic channels. The net photon emission from the chemiluminescence reactions, detected by using a smartphone, is correlated with H2O2 concentrations. With a total reagent volume of 25 μL, the sensor system was able to detect H2O2 concentrations as low as 250 nM. The smartphone based chemiluminescence sensing system has great potential as a point of care diagnostic tool for monitoring nanomolar levels of H2O2 in biological samples. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MICROFLUIDIC devices
*CHEMILUMINESCENCE
*IMIDAZOLES
*PHOTON emission
*BIOSENSORS
Subjects
Details
- Language :
- English
- ISSN :
- 00032654
- Volume :
- 140
- Issue :
- 15
- Database :
- Academic Search Index
- Journal :
- Analyst
- Publication Type :
- Academic Journal
- Accession number :
- 108338166
- Full Text :
- https://doi.org/10.1039/c5an00720h