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High Circulating Frequencies of Tumor Necrosis Factor Alpha- and Interleukin-2-Secreting Human T-Lymphotropic Virus Type 1 (HTLV-1)-Specific CD4[sup +] T Cells in Patients with HTLV-1-Associated Neurological Disease.
- Source :
-
Journal of Virology . Sep2003, Vol. 77 Issue 17, p9716-9722. 7p. 1 Chart, 25 Graphs. - Publication Year :
- 2003
-
Abstract
- Significantly higher frequencies of tumor necrosis factor alpha- and interleukin-2-secreting human T-lymphotropic virus type 1 (HTLV-1)-specific CD4[sup +] T cells were present in the peripheral blood mononuclear cells of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients than in those of asymptomatic carriers with similar provirus loads. The data suggest that HTLV-1-specific CD4[sup +] T cells play a role in the pathogenesis of HAM/TSP. [ABSTRACT FROM AUTHOR]
- Subjects :
- *HIV
*TUMOR necrosis factors
*INTERLEUKIN-2
Subjects
Details
- Language :
- English
- ISSN :
- 0022538X
- Volume :
- 77
- Issue :
- 17
- Database :
- Academic Search Index
- Journal :
- Journal of Virology
- Publication Type :
- Academic Journal
- Accession number :
- 10784056
- Full Text :
- https://doi.org/10.1128/JVI.77.17.9716-9722.2003