Risk of aspirin use plus thrombolysis after acute ischaemic stroke: a further MAST-I analysis. MAST-I Collaborative Group. Multicentre Acute Stroke Trial--Italy.

Focuses on the results of the Multicentre Acute Stroke Trial-Italy (MAST-I) in which the effect of the combination of a thrombolytic and aspirin was assessed. The harmful effect of streptokinase plus aspirin on early case fatality compared with the two drugs given separately; Acute myocardial infarction treatment with aspirin and streptokinase; The role of aspirin in the promotion of intracranial hemorrhage or ischaemic stroke.