Exercise and gallstone disease.

Gallstone disease affects approximately 10-15% of the U.S. population, whereas the prevalence of physical inactivity in the U.S. is approximately 25%. While epidemiological studies have demonstrated a strengthened relation between physical inactivity and gallstone disease, the experimental research has yet to determine a clear underlying physiologic mechanism for such a relation. In this paper the association between physical activity and exercise to gallbladder function and gallstone disease will be examined. Recommendations for future research and the practical implications for the primary prevention of gallstone disease will also be discussed. [ABSTRACT FROM AUTHOR]