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Synthesis and biological activities of potent peptidomimetics selective for somatostatin receptor...

Authors :
Yang, Lihu
Berk, Scott C.
Rohrer, Susan P.
Mosley, Ralph T.
Guo, Liangqin
Underwood, Dennis J.
Arison, Byron H.
Birzin, Elizabeth T.
Hayes, Edward C.
Mitra, Sudha W.
Parmar, Rupa M.
Cheng, Kang
Wu, Tsuei-Ju
Butler, Bridgette S.
Foor, Forrest
Pasternak, Alexander
Pan, Yanping
Silva, Maria
Freidinger, Roger M.
Smith, Roy G.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 09/01/98, Vol. 95 Issue 18, p10836. 6p. 4 Diagrams, 1 Chart, 2 Graphs.
Publication Year :
1998

Abstract

Focuses on a study which synthesized several nonpeptide somatostatin agonists which binded selectively with the somatostatin receptor subtype 2. Distribution of somatostatin throughout the central nervous system; Identification of two biologically active forms of somatostatin; Methodology used to conduct the study; Results of the study.

Details

Language :
English
ISSN :
00278424
Volume :
95
Issue :
18
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
1070501
Full Text :
https://doi.org/10.1073/pnas.95.18.10836