Molecular Dissection of the Contribution of Negatively and Positively Charged Residues in S2, S3, and S4 to the Final Membrane Topology of the Voltage Sensor in the K[sup +] Channel, KAT1.

Discusses the molecular dissection of the contribution of negatively and positively charged residues in S2, S3 and S4 to the final membrane topology of the voltage sensor in the K[sup +] channel, KAT1. Use of in vitro translation and translocation experiments; Indication that Asp[sup 95] assists in the membrane insertion S3-S4.