Reducing the Agonist Activity of Antiandrogens by a Dominant-negative Androgen Receptor Coregulator ARA70 in Prostate Cancer Cells.

Authors :: Rahman, Mujib M.
Miyamoto, Hiroshi
Takatera, Hiroshi
Shuyuan Yeh
Altuwaijri, Saleh
Chawnshang Chang
Source :: Journal of Biological Chemistry. 5/30/2003, Vol. 278 Issue 22, p19619. 8p. 8 Graphs.
Publication Year :: 2003
Abstract: Discusses the role of dominant-negative androgen receptor coagulator 70 in reducing the agonist activity of antiandrogens in prostate cancer cells. Aberrant phosphorylation of the dominant-negative mutant; Androgen response element; Prostate-specific antigen.

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