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Isolation of dammarane saponins from Panax notoginseng by high-speed counter-current chromatography
- Source :
-
Journal of Chromatography A . Aug2003, Vol. 1008 Issue 2, p173. 8p. - Publication Year :
- 2003
-
Abstract
- The Chinese phytomedicinal formulation Sanqi Zongdai Pian, traditionally prepared from crude extracts from roots of Panax notoginseng (Araliaceae), contains highly polar dammarane saponins which were separated at a preparative scale using high-speed counter-current chromatography (HSCCC). In each operation, 283 mg methanolic extract of five tablets was separated and yielded pure 157, 17, 13 and 56 mg of ginsenoside-Rb1, notoginsenoside-R1, ginsenoside-Re and ginsenoside-Rg1, respectively, n-hexane–n-butanol–water (3:4:7, v/v/v) was used for the two-phase solvent system of the HSCCC separation. The chemical structures of three ginsenosides and one notoginsenoside were elaborated by means of electrospray ionization MS–MS and NMR analysis. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00219673
- Volume :
- 1008
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Journal of Chromatography A
- Publication Type :
- Academic Journal
- Accession number :
- 10426326
- Full Text :
- https://doi.org/10.1016/S0021-9673(03)00988-9