Benzyl-N-acetyl-α-D-galactomsaminide Induces a Storage Disease-like Phenotype by Perturbing the Endocytic Pathway.

Reports that the benzyl-N-acetyl-alpha-D-galactosaminide (BG) induces a storage disease-like phenotype by perturbing the endocytic pathway. Association of long-term exposure of cells to BG with the accumulation of apical glycoproteins in cytoplasmic vesicles; Distribution of sialic acid in epithelial cells; Endocytosed membrane proteins in BG0-treated cells.