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Epidermal Growth Factor Receptor Mediates Increased Cell Proliferation, Migration, and Aggregation in Esophageal Keratinocytes in Vitro and in Vivo.

Authors :
Andl, Claudia D.
Mizushima, Takaaki
Nakagawa, Hiroshi
Oyama, Kenji
Harada, Hideki
Chruma, Katerina
Herlyn, Meenhard
Rustgi, Anil K.
Source :
Journal of Biological Chemistry. 1/17/2003, Vol. 278 Issue 3, p1824. 7p. 7 Diagrams, 1 Graph.
Publication Year :
2003

Abstract

Studies how epidermal growth factor receptor (EFGR) mediates increased cell proliferation, migration and aggregation in esophageal keratinocytes in vitro and in vivo. Biological functions of EFGR; Establishment of primary human esophageal squamous epithelial cells; Overexpression in primary esophageal keratinocytes; Interaction with E-cadherin.

Details

Language :
English
ISSN :
00219258
Volume :
278
Issue :
3
Database :
Academic Search Index
Journal :
Journal of Biological Chemistry
Publication Type :
Academic Journal
Accession number :
10394016
Full Text :
https://doi.org/10.1074/jbc.M209148200