Odorless, One-Pot Regio- and Stereoselective Iodothiolationof Alkynes with Sodium Arenesulfinates under Metal-Free Conditionsin Water.

A newlydeveloped regio- and stereoselective radical addition ofalkyne under metal-free conidtions has been disclosed. This chemistry,in which odorless sodium arenesulfinates in place of thiols are usedas the sulfur reagent, provides an efficient, one-pot approach forthe generation of β-iodoalkenyl sulfides, which can be easilyfurther functionalized to derive various alkenes and alkynyl sulfidesrendering this methodology attractive to both synthetic and medicinalchemistry. [ABSTRACT FROM AUTHOR]